Studies of direct mental interaction with living systems suggest that traditional mental healing techniques, such as prayer, may be based on genuine psi-mediated effects. In the future it may be possible to develop enhanced methods of healing based on these phenomena.

Psi may be involved in Murphy's Law: "If anything can go wrong, it will." That is, modern machines based upon sensitive electronic circuits, such as copiers and computers, may at times directly interact with human intention, and as a result, inexplicably fail at inopportune times. Of course, the converse may also be true. That is, the possibility exists to repair, or to control sensitive machines solely by mental means. Such technologies would significantly benefit handicapped persons.

Other potential applications include improved methods of making decisions, of locating missing persons or valuables, and of describing events at locations we cannot go to because of distance, time, or accessibility. This includes the possibility of psi-based historians and forecasters.

Highly developed psi abilities may benefit psychotherapy and other forms of counseling. Psi may be used to provide a statistical edge in the financial markets and in locating archeological treasures.